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Piers Acland QC and Miles Copeland (instructed by Powell Gilbert LLP) for the Claimant and the Third, Fourth and Seventh Parties Richard Meade QC and Kathryn Pickard (instructed by Olswang LLP) for the Defendant Hearing dates: 18-20, 23-24 and 26-27 January 2017 ____________________
(i) The extent to which PVL was known to be a problem in TAVI procedures and the precise nature of likely PVL.
(ii) The extent to which surgical replacement valves were known, i.e. the type of valves sewn into patients during open-heart surgery.
A follow-up review of the literature was published in March 2013 in the Journal of the American College of Cardiology entitled Paravalvular Leak After Transcatheter Aortic Valve Replacement, The New Achilles' Heel? The lead author was Dr Philippe G�n�reux. It included this:
(1) It had to work as valve and so it had to allow blood to flow sufficiently during systole and provide a seal and resist leakage during diastole.
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Common Room
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